Increased prevalence of primary biliary cirrhosis near superfund toxic waste sites

Increased prevalence of antimitochondria

Increased prevalence of antimitochondrial antibodies in first-degree relatives of patients with primary biliary cirrhosis

✍ Konstantinos N. Lazaridis; Brian D. Juran; Gwen M. Boe; Joshua P. Slusser; Mariz 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 187 KB 👁 1 views

Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disorder that can progress to cirrhosis, shortening life expectancy. PBC patients are often asymptomatic, present with biochemical cholestasis, and test positive (>90%) for antimitochondrial antibodies (AMAs) in serum. Although AMA posit