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Increased prevalence of familial autoimmunity in simplex and multiplex families with juvenile rheumatoid arthritis

โœ Scribed by Sampath Prahalad; Edith S. Shear; Susan D. Thompson; Edward H. Giannini; David N. Glass


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
57 KB
Volume
46
Category
Article
ISSN
0004-3591

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โœ Anne Barton; Francine Jury; Stephen Eyre; John Bowes; Anne Hinks; Daniel Ward; J ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 63 KB ๐Ÿ‘ 1 views

## Abstract ## Objective Cytotoxic T lymphocyteโ€“associated antigen 4 (CTLAโ€4) is a negative regulator of T cells and is, therefore, a strong candidate susceptibility gene for T cellโ€“mediated autoimmune diseases. The association of CTLAโ€4 singleโ€nucleotide polymorphisms (SNPs) with rheumatoid arthr