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Increased polyamine concentrations in the cerebrospinal fluid of patients with brain tumors

✍ Scribed by Laurence J. Marton; Olle Heby; Charles B. Wilson

Publisher
John Wiley and Sons
Year
1974
Tongue
French
Weight
290 KB
Volume
14
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

An automated method for the quantitative analysis of the polyamines putrescine, spermidine and spermine in cerebrospinal fluid (CSF) was used to analyze CSF samples from 37 patients with central nervous system (CNS) tumors and from 13p atients without tumors. The putrescine and spermidine concentrations in the CSF of most patients with tumors, particularly those with glioblastomas or medulloblastomas, were elevated when compared with those of non‐tumor‐bearing patients.

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