## Abstract Poly(ADP‐ribose)polymerase (PARP‐1), a nuclear enzyme activated by DNA strand breaks, is involved in DNA repair, aging, inflammation, and neoplastic transformation. In diabetes, reactive oxygen and nitrogen species occurring in response to hyperglycemia cause DNA damages and PARP‐1 acti
Increased poly(ADP-ribose) polymerase activity in lymphoblastoid cell lines from centenarians
✍ Scribed by Marie-Laure Muiras; Marcus Müller; François Schächter; A. Bürkle
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 404 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0946-2716
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