𝔖 Bobbio Scriptorium
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Increased phosphorylation of nuclear phosphoproteins in human lung cancer cells resistant to cisplatin

Book ID
123011631
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
155 KB
Volume
7
Category
Article
ISSN
0169-5002

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## Abstract Resistance to cisplatin‐based chemotherapy is a major cause of treatment failure in human ovarian cancer. Wild‐type __TP53__ status is often, but not always, associated with cisplatin sensitivity, suggesting that additional factors may be involved. Overexpression/activation of the phosp