Oxygen-glucose deprivation activates 5-l
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Cheng-Tan Li; Wei-Ping Zhang; Yun-Bi Lu; San-Hua Fang; Yu-Mei Yuan; Ling-Ling Qi
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Article
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2009
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John Wiley and Sons
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English
⚖ 842 KB
## Abstract 5‐Lipoxygenase (5‐LOX) is a key enzyme catalyzing arachidonic acid to form leukotrienes. We have reported that ischemic‐like injury activates 5‐LOX in PC12 cells; however, the mechanisms are unknown. To determine whether ischemic‐like injury activates 5‐LOX mediated by oxidative stress