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Increased nuclear sizes in senescent human diploid fibroblast cultures

โœ Scribed by Y. Mitsui; E.L. Schneider

Book ID
118876926
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
429 KB
Volume
100
Category
Article
ISSN
0014-4827

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๐Ÿ“œ SIMILAR VOLUMES

Senescence of cultured human diploid fib
Senescence of cultured human diploid fibroblasts. Are mutations responsible?
โœ Radhey S. Gupta ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 691 KB

## Abstract Two predictions of the error/mutation hypothesis of cellular sensecence (Orgel, '73) namely, (a) exponential accumulation of somatic mutations during the replicative lifespan and (b) shortening of culture lifespan upon treatment with mutagens have been examined experimentally in a strai