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Increased nuchal translucency thickness in a fetus at risk for β-thalassaemia

✍ Scribed by George Makrydimas; Ioannis Georgiou; Maria Syrrou; Chariclia Skendou; Dimitrios Lolis

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 85 KB
Volume: 6
Category: Article
ISSN: 1057-0802
DOI: 10.1002/(sici)1520-6661(199709/10)6:5<301::aid-mfm13>3.0.co;2-n

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✦ Synopsis

In Greece and other Mediterranean countries up to 10% of the population are carriers of beta-thalassaemia and this is the most common indication for chorion villus sampling (CVS): Cytogenetic analysis of the samples is not carried out routinely, but is confined only to women aged 35 years or more. In this report we present a case that illustrates how the measurement of fetal nuchal translucency may be useful in selecting the cases where in addition to the DNA analysis for beta-thalassaemia the samples can be tested for chromosomal defects.

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