The pharmacodynamics and kinetics of single oral and intravenous doses of furosemide were studied in 9 patients (mean age 18.5 y) with cystic fibrosis. The diuretic effect of furosemide lasted for 6 h after oral administration and 2 h following intravenous injection of the drug. The patients with cy
✦ LIBER ✦
Increased nonrenal clearance and increased diuretic efficiency of furosemide in cystic fibrosis
✍ Scribed by Alván, G; Beermann, B; Hjelte, L; Lind, M; Lindholm, A; Strandvik, B
- Book ID
- 109844393
- Publisher
- Nature Publishing Group
- Year
- 1988
- Tongue
- English
- Weight
- 436 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0009-9236
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## Communicated by Garry R. Cutting Cystic fibrosis (CF) is a recessive disease caused by mutations of the CF transmembrane conductance regulator (CFTR) gene. The risk of idiopathic chronic pancreatitis (ICP) is increased in individuals who have CFTR genotypes containing a CF-causing mutation plus