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Increased neuronal and glial expression of protein kinase C isoforms in neocortex of transgenic Tg2576 mice with amyloid pathology

✍ Scribed by S. Roßner; G. Mehlhorn; R. Schliebs; V. Bigl

Book ID
109020315
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
455 KB
Volume
13
Category
Article
ISSN
0953-816X

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✍ Steffen Roßner; Jenny Apelt; Reinhard Schliebs; J. Regino Perez-Polo; Volker Big 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 965 KB

## Abstract We measured tissue distribution and expression pattern of the beta‐site amyloid precursor protein (APP)‐cleaving enzyme (BACE) in the brains of transgenic Tg2576 mice that show amyloid pathology. BACE protein was expressed at high levels in brain; at lower levels in heart and liver; and