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Increased methotrexate toxicity due to concurrent probenecid administration

✍ Scribed by Robert E. Kates; Thomas N. Tozer; Donald L. Sorby

Book ID
115772889
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
467 KB
Volume
25
Category
Article
ISSN
0006-2952

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πŸ“œ SIMILAR VOLUMES

Severe renal toxicity due to intermediat
Severe renal toxicity due to intermediate-dose methotrexate
✍ Allistair N. Stark; Graham Jackson; Peter J. Carey; Shahabul Arfeen; Stephen J. πŸ“‚ Article πŸ“… 1989 πŸ› Springer 🌐 English βš– 312 KB

Methotrexate (MTX) is a drug widely used in the treatment of patients with malignant disease. Its well-known side effects include myelosuppression, mucositis and renal damage. These problems are primarily dose-related, tending to occur more frequently when high doses (greater than 1 g/m2) are given.