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Increased liver expression of inflammatory mediators is associated with hepatic insulin resistance in lean, non-diabetic CHC patients

✍ Scribed by E. Vanni; M.L. Abate; E. Gentilcore; C. Elia; R. Gambino; M. Cassader; A. Smedile; M. Rizzetto; G. Marchesini; A. Gastaldelli; E. Bugianesi


Book ID
119229386
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
63 KB
Volume
41
Category
Article
ISSN
1590-8658

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✍ Jie Liu; Angela Ahiekpor; Li Li; Xianxing Li; Patrick Arbuthnot; Michael Kew; Ma πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 French βš– 562 KB

## Abstract Hepatitis B Γ— antigen, or HBxAg, contributes importantly to the pathogenesis of hepatocellular carcinoma (HCC). Given that HBxAg constitutively activates β‐catenin and that upregulated ErbB‐2 promotes β‐catenin signaling in other tumor types, experiments were designed to ask whether HBx