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Increased lipoprotein oxidation in alzheimer’s disease

✍ Scribed by Sven Schippling; Anatol Kontush; Sönke Arlt; Carsten Buhmann; Hans-Jörg Stürenburg; Ulrike Mann; Tomas Müller-Thomsen; Ulrike Beisiegel

Book ID
114277804
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
151 KB
Volume
28
Category
Article
ISSN
0891-5849

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Lipoprotein lipase (LPL) helps transfer lipids from lipoprotein particles to cells. In the brain, LPL is present in Alzheimer's disease (AD) amyloid plaques. LPL binds apolipoprotein E (ApoE) lipoprotein particles and low-density lipoprotein receptor-related protein (LRP), an ApoE receptor. Since po