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Increased leukocyte histamine release with elevated cyclic AMP-phosphodiesterase activity in atopic dermatitis

✍ Scribed by BUTLER, J; CHAN, S; STEVENS, S; HANIFIN, J


Book ID
119056846
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
735 KB
Volume
71
Category
Article
ISSN
1097-6825

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Cyclic adenosine monophosphate phosphodi
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We determined the cyclic adenosine monophosphate phosphodiesterase (cAMP-PDE) activity in peripheral blood mononuclear leucocytes from 100 patients with atopic dermatitis (AD) aged 13-57 years (mean +/- SD, 29.8 +/- 17.7 years). The correlation between cAMP-PDE activity and clinical parameters such