To determine whether chronic overproduction of islet amyloid polypeptide alters beta-cell function, we studied a line of transgenic mice which overexpress islet amyloid polypeptide in their beta-cells. At 3 months of age, these transgenic mice had greater pancreatic content of both islet amyloid pol
✦ LIBER ✦
Increased Insulin Secretion and Glucose Tolerance in Mice Lacking Islet Amyloid Polypeptide (Amylin)
✍ Scribed by Samuel Gebre-Medhin; Hindrik Mulder; Milos Pekny; Gunilla Westermark; Jan Törnell; Per Westermark; Frank Sundler; Bo Ahrén; Christer Betsholtz
- Book ID
- 115582679
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 269 KB
- Volume
- 250
- Category
- Article
- ISSN
- 0006-291X
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