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Increased incidence of cystic fibrosis gene mutations in adults with disseminated bronchiectasis

✍ Scribed by Marigo, Cristina; Benetazzo, Mariagiovanna; Luisetti, Maurizio; Pignatti, Pier Franco; Bombieri, Cristina

Book ID
115480485
Publisher
Oxford University Press
Year
1995
Tongue
English
Weight
480 KB
Volume
4
Category
Article
ISSN
0964-6906

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Asthma is a complex genetic disorder that affects 5% of adults and 10% of children worldwide. The complete characterization of the cystic fibrosis transmembrane conductance regulator (CFTR) gene identified missense mutations in 15% of 144 unrelated adult patients with asthma, but in none of 41 subje