Increased granule cell neurogenesis in the adult dentate gyrus following mossy fiber stimulation sufficient to induce long-term potentiation

Dentate gyrus granule cell firing patter

Dentate gyrus granule cell firing patterns can induce mossy fiber long-term potentiation in vitro

✍ Rajen Mistry; Siobhan Dennis; Matthew Frerking; Jack R. Mellor 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 768 KB

## Abstract Hippocampal granule cells transmit information about behaviorally‐relevant stimuli to CA3 pyramidal cells via mossy fiber synapses. These synapses express a form of long‐term potentiation (mfLTP) that is non‐Hebbian and does not require NMDA receptors. mfLTP is thought to be induced and