Increased Frequency of Venous Thromboembolism with the Combination of Docetaxel and Thalidomide in Patients with Metastatic Androgen-Independent Prostate Cancer
β Scribed by McDonald K. Horne III; William D. Figg; Phil Arlen; James Gulley; Catherine Parker; Nehal Lakhani; Howard Parnes; William L. Dahut
- Book ID
- 115048738
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 30 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0277-0008
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## Abstract ## BACKGROUND. The addition of diethylstilbestrol to docetaxel modified tubulin composition and improved the response of prostate cancer to chemotherapy in preclinical models. An attempt was made to recapitulate the observations in a clinical trial. ## METHODS. Twentyβnine patients w
## Abstract ## BACKGROUND. Survival in patients with metastatic, chemotherapyβnaive, androgenβindependent prostate cancer (AIPC) is improved with 10 to 12 cycles of docetaxelβcontaining chemotherapy but further management is undefined. In the current study, the authors examined retreatment with th