Increased frequencies of sister chromatid exchanges at common fragile sites (1)(q42) and (19)(q13)

Induction of distamycin A-inducible rare

Induction of distamycin A-inducible rare fragile sites and increased sister chromatid exchanges at the fragile site

✍ Hideo Tsuji; Akitsu Hitomi; Ei-ichi Takahashi; Motoi Murata; Tatsuro Ikeuchi; Ko 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 832 KB

Expression of distamycin A-inducible rare fragile sites by AT-specific DNA-ligands was examined in lymphoblastoid cell lines derived from heterozygous carriers for the fra(8)(q24), fra(16)(pl2), and fra(16)(q22) sites. The sensitivity of fragile site expression to the inducers was different at these