Increased extracellular levels of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in minor salivary glands of patients with Sjögren's syndrome

Increased expression of the novel proinf

Increased expression of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in skin lesions of patients with lupus erythematosus

✍ Karin Popovic; Monica Ek; Alexander Espinosa; Leonid Padyukov; Helena Erlandsson 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 318 KB 👁 2 views

## Abstract ## Objective To investigate the role of the novel cytokine high mobility group box chromosomal protein 1 (HMGB‐1) in the pathogenesis of cutaneous lupus erythematosus (CLE). ## Methods Punch biopsy specimens of lesional and unaffected skin from 10 patients with CLE and 3 healthy cont