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Increased expression ofl-amino acid transporters in balloon cells of tuberous sclerosis

✍ Scribed by Byung-Chan Lim; Kyu-Young Cho; Joon-Seop Lim; Rae-Seop Lee; Hyung-Seok Kim; Myeong-Kyu Kim; Jae-Hyoo Kim; Young-Jong Woo; Jong-Keun Kim; Do Kyung Kim; Hyung-Ihl Kim; Kyung-Wha Lee; Min-Cheol Lee


Publisher
Springer
Year
2010
Tongue
English
Weight
340 KB
Volume
27
Category
Article
ISSN
0256-7040

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## Abstract Individuals with tuberous sclerosis complex (TSC) develop central nervous system abnormalities that may reflect astrocyte dysfunction. In an effort to model astrocyte dysfunction in TSC, we generated mice lacking __Tsc1__ (hamartin) expression in astrocytes and demonstrated that __Tsc1_