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Increased expression of T-bet in circulating B cells from a patient with multiple sclerosis and celiac disease

✍ Scribed by Giovanni Frisullo; Viviana Nociti; Raffaele Iorio; Agata Katia Patanella; Alessandro Marti; Giovanni Cammarota; Massimiliano Mirabella; Pietro Attilio Tonali; Anna Paola Batocchi


Book ID
118448832
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
608 KB
Volume
69
Category
Article
ISSN
0198-8859

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## Abstract Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system, and it is considered to be a T helper 1 (Th1) cell‐mediated autoimmune disease. T‐bet has been identified as a key transcription factor for the development of Th1 cells and the inducti