Increased Expression of Sodium Channel Subunit Nav1.1 in the Injured Dorsal Root Ganglion After Peripheral Nerve Injury

Altered expression of sodium channel dis

Altered expression of sodium channel distribution in the dorsal root ganglion after gradual elongation of rat sciatic nerves

✍ Katsunori Ohno; Atsushi Yokota; Shinji Hirofuji; Kiyoto Kanbara; Hisashi Ohtsuka 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 246 KB

To elucidate the pathophysiological mechanisms underlying chronic nerve-stretch injury, we gradually lengthened rat femurs by 15 mm at the rate of 0.5 mm/day (group L, n = 13). The control groups comprised sham-operated (group S, n = 10) and naive (group N, n = 8) rats. Immediately after the lengthe