Pancreatic juice is a promising type of diagnostic sample for pancreatic cancer, and members of the mucin (MUC) family are diagnostic candidates. To evaluate the utility of MUC family members as diagnostic markers, we measured MUC mRNA expression in pancreatic tissues and pancreatic juice obtained f
Increased expression of MUC1 in advanced pancreatic cancer
β Scribed by Yuji Hinoda; Yoshito Ikematsu; Michiko Horinochi; Shuji Sato; Kotaro Yamamoto; Tomoko Nakano; Mikiko Fukui; Yutaka Suehiro; Yuichiro Hamanaka; Yoshiro Nishikawa; Hideo Kida; Shinji Waki; Masaaki Oka; Kohzoh Imai; Suguru Yonezawa
- Publisher
- Springer Japan
- Year
- 2003
- Tongue
- English
- Weight
- 246 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0944-1174
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## BACKGROUND. Mucins are high molecular weight glycoproteins that are produced by various epithelial cells including those found in the pancreas. MUC1 and MUC2 are two well characterized mucin antigens. The objective of the current study was to examine the pattern of phenotypic expression of MUC1
The epithelial expression of apomucins MUCl, MUC2, MUC3, and MUC5/6 was examined in normal pancreas and in pancreatic lesions, using immunohistochemical methods. In normal pancreas (n=5), MUCl apomucin was expressed in ducts and some acini, but there was no expression of MUC2, MUC3, or MUC5/6. In ch