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Increased expression of Ia antigens on thymocytes from late preleukemic and leukemic AKR mice

✍ Scribed by Christoph C. Zielinski; Syamal K. Datta; Samuel D. Waksal


Publisher
Springer-Verlag
Year
1981
Tongue
English
Weight
471 KB
Volume
14
Category
Article
ISSN
0093-7711

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## Abstract BALB/c mice rendered chimeric at birth by injection of 10^8^ (A/J Γ— BALB/c)F^1^ spleen cells develop a lupus‐like autoimmune disease linked to the activation of donor B cells by host T cells. As __in vitro__ studies previously indicated that interleukin 4 (IL4) was a mediator of the int