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Increased expression of cyclooxygenase-2 (COX-2) in gastric carcinoma and in the gastric mucosa of healthy first-degree relatives

โœ Scribed by Miehlke, Stephan; Yu, Jin; Szokodi, Daniel; Kuhlisch, Eberhard; Wuendisch, Thomas; Ebert, Matthias; Wehrmann, Ursula; Saeger, Hans Detlev; Stolte, Manfred; Ehninger, Gerhard; Bayerdoerffer, Ekkehard

Book ID
122831852
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
181 KB
Volume
118
Category
Article
ISSN
0016-5085

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## BACKGROUND. Studies not considering Helicobacter pylori infection have suggested the presence of a hereditary risk for gastric carcinoma. However, other studies have identified intrafamilial clustering of H. pylori infection as a causal factor in gastric carcinogenesis. This prompted the authors