Objective. To investigate the activation and expression of CCAAT/enhancer-binding proteins (C/EBP), especially C/EBP and -␦, in rheumatoid synovium, and their pathogenic implications in rheumatoid arthritis (RA). Methods. The activation of C/EBP and -␦ was assessed in synovial tissues from patient
✦ LIBER ✦
Increased expression of CCAAT/enhancer binding protein-β and -δ and monocyte chemoattractant protein-1 genes in aortas from hyperinsulinaemic rats
✍ Scribed by Y. Sato; Y. Nishio; O. Sekine; K. Kodama; Y. Nagai; T. Nakamura; H. Maegawa; A. Kashiwagi
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 359 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0012-186X
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CCAAT-enhancer-binding protein beta (CEBPB) is a pluripotent transcription factor that controls inflammation, proliferation, and differentiation. We recently reported a role for CEBPB during matrix metalloproteinase (MMP) gene expression, but the mechanisms involved are poorly understood. To address