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Increased efficacy of acyclovir-loaded microparticles against herpes simplex virus type 1 in cell culture

✍ Scribed by E.Ga de Jalón; M.J. Blanco-Prı́eto; P. Ygartua; S. Santoyo


Book ID
117639480
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
302 KB
Volume
56
Category
Article
ISSN
0939-6411

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Inhibition by acyclovir of herpes simple
✍ Dr Louis S. Kucera; Phillip A. Furman; Gertrude B. Elion 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 525 KB

## Abstract Rat embryo fibroblasts (REF) morphologically transformed by herpes simplex virus type 2 (HSV‐2) and tumor‐derived cells were tested for ability to grow in the presence of 9‐(2‐hydroxyethoxymethyl) guanine (acyclovir). Results indicated that the effective dose of acyclovir (ACV) required