## Abstract Most breast cancer metastases in bone form osteolytic lesions, but the mechanisms of tumor‐induced bone resorption and destruction are not fully understood. Although it is well recognized that Wnt/β‐catenin signaling is important for breast cancer tumorigenesis, the role of this pathway
✦ LIBER ✦
Increased Dickkopf-1 expression in breast cancer bone metastases
✍ Scribed by Voorzanger-Rousselot, N; Goehrig, D; Journe, F; Doriath, V; Body, J J; Clézardin, P; Garnero, P
- Book ID
- 109999260
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 179 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0007-0920
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## Abstract Periostin, a matricellular protein, is overexpressed in the stroma of several cancers. The aim of our study was to investigate more specifically whether periostin expression is associated with bone metastases from breast cancer and to determine its source in the affected bone. Nude mice