To generate non-small cell lung cancer (NSCLC)-reactive lymphocytes, we transfected an HLA-A2-expressing human NSCLC line (1355) with the cDNA encoding the lymphocyte co-stimulatory molecule CD80. Following selection in G418, 1355.7 demonstrated stable cell-surface expression of CD80. Allogeneic mix
✦ LIBER ✦
Increased Cytotoxicity of 2′,2′-Difluoro-2′-deoxycytidine in Human Leukemic Cell-Lines After a Preincubation with Cyclopentenyl Cytosine
✍ Scribed by A. C. Verschuur; A. H. Van Gennip; R. Leen; A. B. P. Van Kuilenburg
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 8 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract It has been previously demonstrated that human carcinomas express interleukin‐2 receptor (IL‐2R) α, β, and γ chains. The β and γ chains of IL‐2R have intermediate binding affinity for IL‐2 and are responsible for the intracellular signaling cascades after IL‐2 stimulation. IL‐2Rα lacks