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Increased Cystatin C in Astrocytes of Transgenic Mice Expressing the K670N-M671L Mutation of the Amyloid Precursor Protein and Deposition in Brain Amyloid Plaques

โœ Scribed by Tiana Steinhoff; Eva Moritz; M.Axel Wollmer; M.Hasan Mohajeri; Stefan Kins; Roger M. Nitsch


Book ID
115641636
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
450 KB
Volume
8
Category
Article
ISSN
0969-9961

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## Abstract Numerous transgenic mouse models for Alzheimer's disease (AD) have been generated to recapitulate the histological pathogenesis and behavioral phenotypes of AD brain. However, none of the existing models exhibits the full spectrum of AD symptoms, nor have all of the traits mimicked by t