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Increased cyclic nucleotide phosphodiesterase activity in leukaemic lymphocytes

✍ Scribed by HAIT, WILLIAM N.; WEISS, BENJAMIN


Book ID
109698066
Publisher
Nature Publishing Group
Year
1976
Tongue
English
Weight
371 KB
Volume
259
Category
Article
ISSN
0028-0836

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Cyclic nucleotide phosphodiesterase acti
✍ M. T. TΓ©llez-IΓ±Γ³n; H. N. Torres πŸ“‚ Article πŸ“… 1982 πŸ› Springer 🌐 English βš– 364 KB

Erythrocyte soluble phosphodiesterase activities show at least two interconvertible states: "aggregated' and "non-aggregated'. In the former state the existence of a high affinity component for cyclic AMP is favoured and the system is more active with cyclic AMP than with cyclic GMP as substrate. Wh