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Increased concentration of metronidazole and its hydroxy metabolite in colon cancer in women

✍ Scribed by Sadowska, Anna; Kędra, Bogusław; Cepowicz, Dariusz; Rodziewicz, Lech; Fiedorowicz, Anna; Prokopiuk, Sławomir; Miltyk, Wojciech; Car, Halina

Book ID
122207514
Publisher
Elsevier
Year
2012
Tongue
English
Weight
135 KB
Volume
64
Category
Article
ISSN
1734-1140

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## Abstract Sulindac is a nonsteroidal antiinflammatory drug that has been demonstrated to be a potent chemopreventive agent against colorectal cancer in both human and animal models. __In vivo__, sulindac may be reversibly reduced to the active antiinflammatory compound, sulindac sulfide, or irrev