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Increased cell death in HeLa and SH-SY5Y cells after knocking down FUS

✍ Scribed by Amadeus Gladbach; Lars Ittner; Yazi Ke; Janet van Eersel; Jurgen Gotz; Nikolas Haass

Book ID
118467158
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
51 KB
Volume
7
Category
Article
ISSN
1552-5260

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## Abstract Free cytoplasmic dopamine may be involved in the genesis of neuronal degeneration in Parkinson's disease and other such diseases. We used SH‐SY5Y human neuroblastoma cells to study the effect of dopamine on cell death, activation of stress‐induced pathways, and expression of α‐synuclein