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Increased cancericidal activity of PTT.119; a new synthetic bis-(2-chloroethyl)amino-l-phenylalanine derivative with carrier amino acids

โœ Scribed by Mary Jane Yagi; Mohammed Zanjani; James F. Holland; J. George Bekesi

Book ID
104684887
Publisher
Springer
Year
1984
Tongue
English
Weight
574 KB
Volume
12
Category
Article
ISSN
0344-5704

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Increased cancericidal activity of PTT.1
Increased cancericidal activity of PTT.119, a new synthetic bis-(2-chloroethyl)amino-l-phenylalanine derivative with carrier amino acids
โœ Mary Jane Yagi; J. George Bekesi; M. D. Daniel; James F. Holland; A. Barbieri ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer ๐ŸŒ English โš– 701 KB

A new synthetic tripeptide (p-F-Phe-m-bis-(2-chloroethyl)amino-Phe-Met ethoxy HCl), PTT.119, was demonstrated to have significant cancericidal activity against seven in vitro tumor cell lines of different origins and etiologies and against primary human AMML, ALL, and hairy cell leukemias. Viabiliti