Increased c-Met tyrosine kinase expression in segmental renal dysplasia

Increased expression of fibroblast growt

Increased expression of fibroblast growth factors in segmental renal dysplasia

✍ H. Shima; H. Tazawa; P. Puri 📂 Article 📅 2000 🏛 Springer-Verlag 🌐 English ⚖ 307 KB

Radiation stimulates HGF receptor/c-Met

Radiation stimulates HGF receptor/c-Met expression that leads to amplifying cellular response to HGF stimulation via upregulated receptor tyrosine phosphorylation and MAP kinase activity in pancreatic cancer cells

✍ Li-Wu Qian; Kazuhiro Mizumoto; Naoki Inadome; Eishi Nagai; Norihiro Sato; Kunio 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 400 KB

Hepatocyte growth factor (HGF) is a stromal-derived cytokine that plays a crucial role in invasion and metastasis of tumor cells through the interaction with HGF receptor, c-Met, which is frequently overexpressed in pancreatic cancer. The present study was designed to investigate the change in HGF r