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Increased binding of polymeric λ-IgA to cultured human mesangial cells in IgA nephropathy

✍ Scribed by Lai, Kar Neng; To, Wah Yuen; Li, Philip K T; Leung, Joseph C K


Book ID
109884336
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
725 KB
Volume
49
Category
Article
ISSN
0085-2538

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Increased sialylation of polymeric λ-IgA
✍ Joseph C.K. Leung; Sydney C.W. Tang; Daniel T.M. Chan; Sing Leung Lui; Kar Neng 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 349 KB

The mechanism of mesangial IgA deposition is poorly understood in IgA nephropathy (IgAN). Abnormal glycosylation of carbohydrate moieties in the hinge region of the IgA molecule has recently attracted much attention. In this report, we studied galactosylation and sialylation profiles in κand λ-IgA 1