Increased sialylation of polymeric λ-IgA
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Joseph C.K. Leung; Sydney C.W. Tang; Daniel T.M. Chan; Sing Leung Lui; Kar Neng
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Article
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2002
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John Wiley and Sons
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English
⚖ 349 KB
The mechanism of mesangial IgA deposition is poorly understood in IgA nephropathy (IgAN). Abnormal glycosylation of carbohydrate moieties in the hinge region of the IgA molecule has recently attracted much attention. In this report, we studied galactosylation and sialylation profiles in κand λ-IgA 1