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Increased binding of liposomes to cells by electric treatment

✍ Scribed by Leonid V. Chernomordik; Demetrios Papahadjopoulos; Tian Y. Tsong


Book ID
115729721
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
752 KB
Volume
1070
Category
Article
ISSN
0005-2736

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Polymer shielded liposomes were investigated as detoxifying agents for the weak bases imipramine and dosulepin and the diprotic drug opipramol. In vitro binding measurements in the presence of human serum samples revealed that the liposomes reduced the free drug concentration of the weak bases (corr