Increased antigen presenting cell-mediated T cell activation in mice and patients without the autoimmune regulator
✍ Scribed by Chris Ramsey; Signe Hässler; Per Marits; Olle Kämpe; Charles D. Surh; Leena Peltonen; Ola Winqvist
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 416 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Background Heparanase is an endo‐β‐D‐glucuronidase that cleaves heparan sulfate saccharide chains. The enzyme promotes cell adhesion, migration and invasion, and was shown to play a significant role in cancer metastasis and angiogenesis. ## Methods The present study focuses on the
We have investigated the effect of pre-treatment with the anti-cancer drugs cisplatin and etoposide on the susceptibility of P815 murine mastocytoma cells to lysis by murine spleen-derived anti-CD3-activated killer-T (AK-T) cells. A 20 hr pre-treatment with cisplatin (0.2-2 microg/ml) or etoposide (