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Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1

✍ Scribed by Duff, Karen; Eckman, Chris; Zehr, Cindy; Yu, Xin; Prada, Cristian-Mihail; Perez-tur, Jordi; Hutton, Mike; Buee, Luc; Harigaya, Yasuo; Yager, Debra

Book ID: 109798198
Publisher: Nature Publishing Group
Year: 1996
Tongue: English
Weight: 952 KB
Volume: 383
Category: Article
ISSN: 0028-0836
DOI: 10.1038/383710a0

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## Abstract A recent report showed that the accumulation of α‐synuclein (α‐syn) was detected in the brains of one‐third of Alzheimer's disease and Down syndrome patients. However, the relationship between amyloid‐β protein (Aβ) and α‐syn remains unclear. We analyzed the relation between the mutatio