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Increase of hexobarbital sleeping time and inhibition of drug metabolism by the major metabolite of diphenylhydantoin

✍ Scribed by Salomon A. Stavchansky; William C. Lubawy; Harry B. Kostenbauder

Book ID
118936425
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
173 KB
Volume
14
Category
Article
ISSN
0024-3205

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πŸ“œ SIMILAR VOLUMES

Heredity of hexobarbital sleeping time a
Heredity of hexobarbital sleeping time and efficiency of drug metabolism in Wistar and Sprague-Dawley rats
✍ I. Gut; B. A. Becker πŸ“‚ Article πŸ“… 1975 πŸ› Springer-Verlag 🌐 English βš– 602 KB

Nature of considerable variability of hexobarbital sleeping time and drug metabolism efficiency within a single strain of rats was investigated. Wistar or Sprague-Dawley rats with shorter than average hexobarbital sleeping time had also higher rates of in vitro hepatic microsomal metabolism of hexob