Increase in the number of histone genes in case of their deficiency in Drosophila melanogaster
β Scribed by Chernyshev, A. I. ;Bashkirov, V. N. ;Leibovitch, B. A. ;Khesin, R. B.
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 720 KB
- Volume
- 178
- Category
- Article
- ISSN
- 0026-8925
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β¦ Synopsis
We have determined the number of histone structural genes in D. melanogaster heterozygotes for two different deficiencies of a histone locus in the 2d chromosome. The results indicate a possibility of histone genes increasing in number in the case of their deficiency through magnification and compensation, as has been shown for rRNA genes by other authors.
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The penetrance in heterozygotes of vestigial mutants was analysed. Two ,genetic modifier systems, one enhancing, the other diminishing the penetrance of vg in heterozygotes were postdated. Both modifiers were found either in the wild or in the mutant strains, and are located on the X chromosome. Fr
The deficiency of the 38B-40 region containing histone genes in one of the 2nd chromosomes of D. melanogaster triploid intersexes increases the template activity of X-chromosomes both in vivo and in vitro without noticeably affecting autosome activity. This deficiency in the heterozygous state inhib