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Increase in nitric oxide in the hypoxic–ischemic neonatal rat brain and suppression by 7-nitroindazole and aminoguanidine

✍ Scribed by Yoshihisa Higuchi; Haruo Hattori; Toshiaki Kume; Masahiro Tsuji; Akinori Akaike; Kenshi Furusho


Book ID
119414337
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
73 KB
Volume
342
Category
Article
ISSN
0014-2999

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Iron can contribute to hypoxic-ischemic brain damage by catalyzing the formation of free radicals. The immature brain has high iron levels and limited antioxidant defenses. The objective of this study was to describe the early alterations in nonheme iron histochemistry following a hypoxic-ischemic (