Increase in heme oxygenase-1 levels ameliorates renovascular hypertension
✍ Scribed by Botros, Fady T.; Schwartzman, Michal L.; Stier, Charles T.; Goodman, Alvin I.; Abraham, Nader G.
- Book ID
- 109067500
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 259 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0085-2538
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📜 SIMILAR VOLUMES
Heme oxygenase (HO) catalyzes the conversion of heme into biliverdin, iron, and carbon monoxide (CO). Two isoforms of HO have been identified: the inducible HO-1 and the constitutive HO-2. CO, like nitric oxide, is an endogenous vasodilator that could contribute to modulation of systemic and local v
Vascular heme oxygenase (HO) regulates vascular tone in normal conditions and in some pathologic circumstances (e.g., sepsis). However, its possible role in the pathogenesis of arterial vasodilation in cirrhosis is unknown. To address this question, the expression and activity of HO in arterial vess