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Incorporation of non-proteolytic proteins by murine α2-macroglobulin

✍ Scribed by Gourab Bhattacharjee; Hanne Grøn; Salvatore V Pizzo

Book ID
114149940
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
296 KB
Volume
1432
Category
Article
ISSN
0167-4838

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Alpha-2-macroglobulin (a,M) in the rat and human brain is an acute-phase protein synthesized primarily by astrocytes, and it has been implicated in Alzheimer's disease and other neuropathological processes. The activated forms of aZM, but not the native form, can suppress the neurite outgrowth of th