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Incorporation of label from 5-fluoroorotate into non-ribosomal cytoplasmic RNA in rat liver

โœ Scribed by Alois Cihak; Henry C. Pitot

Book ID
117980235
Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
268 KB
Volume
6
Category
Article
ISSN
0014-5793

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The cytotoxicity of 5-FUra has been related to its incorporation into RNA. In a model of secondary liver cancer in the rat, the incorporation of 5-FUra into the acid-soluble fraction, RNA and DNA of several normal tissues and an adenocarcinoma of the colon transplanted to the liver was determined. A