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Incomplete B Cell Tolerance to Cartilage Oligomeric Matrix Protein in Mice

✍ Scribed by Geng, Hui; Nandakumar, Kutty Selva; Xiong, Li; Jie, Rui; Dong, Jiahui; Holmdahl, Rikard


Book ID
121710678
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
591 KB
Volume
65
Category
Article
ISSN
0004-3591

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Cartilage oligomeric matrix protein indu
✍ Stefan Carlsen; Kutty Selva Nandakumar; Johan BΓ€cklund; Jens Holmberg; Malin Hul πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 207 KB

## Abstract ## Objective To develop a new mouse model for arthritis using cartilage oligomeric matrix protein (COMP) and to study the role of major histocompatibility complex (MHC) and __Ncf1__ genes in COMP‐induced arthritis (COMPIA). ## Methods Native (pentameric) and denatured (monomeric) COM