Inclusion Complexes of Dimethyl 2,6-Naphthalenedicarboxylate with α- and β-Cyclodextrins in Aqueous Medium: Thermodynamics and Molecular Mechanics Studies
✍ Scribed by Cervero, Marta; Mendicuti, Francisco
- Book ID
- 120243722
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 173 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0022-3654
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📜 SIMILAR VOLUMES
Molecular mechanics calculations were employed to study the inclusion of 2-methyl naphthoate in alpha- and beta-cyclodextrin in vacuo and in the presence of water as a solvent. The driving forces for complexation are dominated by nonbonded van der Waals host:guest interactions in both environments.
The inclusion complex formation of alpha-cyclodextrin (alpha-CyD), beta-cyclodextrin (beta-CyD), and 2-hydroxylpropyl-beta-cyclodextrin (HP-beta-CyD) with an angiotensin converting enzyme inhibitor, captopril, in aqueous solution was studied by (1)H- and (13)C-nuclear magnetic resonance spectroscopi