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Inclusion Complexation of Loratadine with Natural and Modified Cyclodextrins: Phase Solubility and Thermodynamic Studies

✍ Scribed by L. Omar; M. I. El-Barghouthi; N. A. Masoud; A. A. Abdoh; M. M. Al Omari; M. B. Zughul; A. A. Badwan


Publisher
Springer US
Year
2007
Tongue
English
Weight
427 KB
Volume
36
Category
Article
ISSN
0095-9782

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Phase solubility and inclusion complex o
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Phase-solubility techniques were used to assess the formation of inclusion complex between itraconazole and beta-cyclodextrin. The stability constant and free energies of transfer of itraconazole from aqueous solution to the cavity of beta-cyclodextrin were calculated. Itraconazole solubility in sup