Including known covariates can reduce power to detect genetic effects in case-control studies

The power of independent types of geneti

The power of independent types of genetic information to detect association in a case-control study design

✍ Sungho Won; Robert C. Elston 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 347 KB 👁 1 views

## Abstract There have been many single nucleotide polymorphism‐based tests suggested for association analysis in a case‐control design. The possible evidence for association comprises three types of information: differences between cases and controls in allele frequencies, in parameters for Hardy